This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.,EREG,EPR,ER,Ep,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,EGF,Cardiovascular,Angiogenesis,EREG