AI317360 antibody, Ssc2 antibody, SSC2 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 antibody, ELOVL fatty acid elongase 2 antibody, Elovl2 antibody, ELOVL2 antibody
背景
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA, acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6 acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.,SSC2,ELOVL2,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Heart,Lipids,Fatty Acids,Cardiovascular diseases,Heart disease,ELOVL2