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ELANE 抗体

ELANE 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266912
发货至: 中国
  • 抗原 See all ELANE 抗体
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    适用
    • 69
    • 5
    • 4
    宿主
    • 51
    • 16
    • 5
    • 1
    克隆类型
    • 49
    • 24
    单克隆
    标记
    • 41
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ELANE antibody is un-conjugated
    应用范围
    • 35
    • 34
    • 14
    • 10
    • 7
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    Neutrophil Elastase (ELANE) Rabbit mAb
    交叉反应
    人, 小鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Neutrophil Elastase (ELANE)
    亚型
    IgG
    Top Product
    Discover our top product ELANE Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    别名
    ELANE (ELANE 产品)
    别名
    ELA2 antibody, GE antibody, HLE antibody, HNE antibody, NE antibody, PMN-E antibody, SCN1 antibody, Ela2 antibody, F430011M15Rik antibody, ela2 antibody, ELANE antibody, elastase, neutrophil expressed antibody, proteinase 3 antibody, ELANE antibody, Elane antibody, prtn3 antibody
    背景
    Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016],ELA2, GE, HLE, HNE, NE, PMN-E, SCN1,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Signal Transduction,ELANE
    分子量
    29kDa
    基因ID
    1991
    UniProt
    P08246
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