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EGLN1 抗体 (AA 1-426)
KO Validated
EGLN1
适用: 人
WB, IHC, IF
宿主: 兔
Polyclonal
unconjugated
EGLN1抗体详情
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抗原
See all EGLN1 抗体
EGLN1
(Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
抗原表位
All epitopes for EGLN1 抗体
AA 1-426
适用
All reactivities for EGLN1 抗体
人
宿主
All hosts for EGLN1 抗体
兔
克隆类型
All clonalities for EGLN1 抗体
多克隆
标记
All conjugates for EGLN1 抗体
This EGLN1 antibody is un-conjugated
应用范围
All applications for EGLN1 抗体
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
原理
[KO Validated] PHD2 Rabbit pAb
序列
MANDSGGPGG PSPSERDRQY CELCGKMENL LRCSRCRSSF YCCKEHQRQD WKKHKLVCQG SEGALGHGVG PHQHSGPAPP AAVPPPRAGA REPRKAAARR DNASGDAAKG KVKAKPPADP AAAASPCRAA AGGQGSAVAA EAEPGKEEPP ARSSLFQEKA NLYPPSNTPG DALSPGGGLR PNGQTKPLPA LKLALEYIVP CMNKHGICVV DDFLGKETGQ QIGDEVRALH DTGKFTDGQL VSQKSDSSKD IRGDKITWIE GKEPGCETIG LLMSSMDDLI RHCNGKLGSY KINGRTKAMV ACYPGNGTGY VRHVDNPNGD GRCVTCIYYL NKDWDAKVSG GILRIFPEGK AQFADIEPKF DRLLFFWSDR RNPHEVQPAY ATRYAITVWY FDADERARAK VKYLTGEKGV RVELNKPSDS VGKDVF
交叉反应
人, 小鼠, 大鼠
产品特性
Polyclonal Antibodies
纯化方法
Affinity purification
质量等级
KO Validated
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-426 of human PHD2 (NP_071334.1).
亚型
IgG
Alternatives
(show)
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (C-Term) antibody
EGLN1
适用: 人, 小鼠, 大鼠, 兔, 猴, 犬, Cow, 豚鼠, 马, 小鸡, Pig
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
EGLN1目标详情
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抗原
EGLN1
(Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
别名
EGLN1 (EGLN1 产品 )
别名
EGLN1 antibody, egln2 antibody, phd2 antibody, zgc:92314 antibody, AI503754 antibody, C1orf12 antibody, HIF-PH2 antibody, HPH-2 antibody, Hif-p4h-2 antibody, ORF13 antibody, Phd2 antibody, SM-20 antibody, PHD-2 antibody, PHD2 antibody, ECYT3 antibody, HIFPH2 antibody, HPH2 antibody, SM20 antibody, ZMYND6 antibody, egl nine homolog 1 (C. elegans) antibody, egl-9 family hypoxia inducible factor 1 antibody, egl-9 family hypoxia-inducible factor 1 S homeolog antibody, egl-9 family hypoxia-inducible factor 1b antibody, egl-9 family hypoxia-inducible factor 1 antibody, EGLN1 antibody, egln1.S antibody, egln1b antibody, Egln1 antibody
背景
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).,EGLN1,C1orf12,ECYT3,HALAH,HIF-PH2,HIFPH2,HPH-2,HPH2,PHD2,SM20,ZMYND6,Epigenetics & Nuclear Signaling,Cancer,Invasion and Metastasis,Endocrine & Metabolism,Cardiovascular,Angiogenesis,Hypoxia,EGLN1
分子量
36kDa/43kDa/46kDa
基因ID
54583
UniProt
Q9GZT9
途径
cAMP Metabolic Process , Warburg Effect
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