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E2F1 抗体

E2F1 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266873
发货至: 中国
  • 抗原 See all E2F1 抗体
    E2F1 (E2F Transcription Factor 1 (E2F1))
    适用
    • 187
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    宿主
    • 190
    • 12
    • 2
    克隆类型
    • 181
    • 23
    单克隆
    标记
    • 90
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    This E2F1 antibody is un-conjugated
    应用范围
    • 175
    • 88
    • 67
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    • 48
    • 30
    • 22
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    • 15
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    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    E2F1 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human E2F1.
    亚型
    IgG
    Top Product
    Discover our top product E2F1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    E2F1 (E2F Transcription Factor 1 (E2F1))
    别名
    E2F1 (E2F1 产品)
    背景
    The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008],E2F-1,RBAP1,RBBP3,RBP3,E2F1,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,G1/S Checkpoint,Signal Transduction,Transcription Factors,Tumor suppressors,E2F1
    分子量
    46kDa
    基因ID
    1869
    UniProt
    Q01094
    途径
    p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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