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DLAT 抗体

DLAT 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266767
发货至: 中国
  • 抗原 See all DLAT 抗体
    DLAT (Dihydrolipoyl Transacetylase (DLAT))
    适用
    • 58
    • 22
    • 19
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 54
    • 7
    克隆类型
    • 56
    • 5
    单克隆
    标记
    • 32
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DLAT antibody is un-conjugated
    应用范围
    • 43
    • 26
    • 23
    • 13
    • 9
    • 8
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB)
    原理
    DLAT Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human DLAT
    亚型
    IgG
    Top Product
    Discover our top product DLAT Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DLAT (Dihydrolipoyl Transacetylase (DLAT))
    别名
    DLAT (DLAT 产品)
    别名
    DLAT antibody, Dmel\\CG5261 antibody, EP(2)0816 antibody, EP816 antibody, anon-WO0118547.121 antibody, DLTA antibody, PDC-E2 antibody, PDCE2 antibody, wu:fc14f10 antibody, wu:fc21f08 antibody, wu:fc86g11 antibody, wu:fj57d06 antibody, 6332404G05Rik antibody, midline uncoordinated antibody, dihydrolipoamide S-acetyltransferase L homeolog antibody, dihydrolipoamide S-acetyltransferase antibody, dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) antibody, muc antibody, dlat.L antibody, DLAT antibody, Dlat antibody, dlat antibody
    背景
    This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.[provided by RefSeq, Oct 2009],DLTA, PDC-E2, PDCE2,Cancer,Carbohydrate metabolism,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,DLAT
    分子量
    69kDa
    基因ID
    1737
    UniProt
    P10515
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