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DNER 抗体 (AA 140-240)

DNER 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7266727
发货至: 中国
  • 抗原 See all DNER 抗体
    DNER (delta/notch-Like EGF Repeat Containing (DNER))
    抗原表位
    • 15
    • 14
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-240
    适用
    • 55
    • 14
    • 11
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 50
    • 3
    • 2
    • 1
    克隆类型
    • 53
    • 3
    多克隆
    标记
    • 21
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNER antibody is un-conjugated
    应用范围
    • 29
    • 28
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    DNER Rabbit pAb
    序列
    PATGWTESMA PRQLQPVPAT QEPDKILPRS QATVTLPTWQ PKTGQKVVEM KWDQVEVIPD IACGNASSNS SAGGRLVSFE VPQNTSVKIR QDATASLILL W
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DNER (NP_620711.3).
    亚型
    IgG
    Top Product
    Discover our top product DNER Primary Antibody
  • 应用备注
    WB,1:200 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DNER (delta/notch-Like EGF Repeat Containing (DNER))
    别名
    DNER (DNER 产品)
    别名
    UNQ26 antibody, bet antibody, A930026D19Rik antibody, BET antibody, Bret antibody, delta/notch like EGF repeat containing antibody, delta and Notch-like epidermal growth factor-related receptor antibody, delta/notch-like EGF repeat containing antibody, DNER antibody, LOC540552 antibody, Dner antibody
    背景
    DNER (Delta/Notch-like EGF-related receptor), also known as BET (brain-specific EGF-like transmembrane protein), is a type I transmembrane glycoprotein of the Notch/Delta family . In the mouse, DNER has been detected as 90, 120 and 150 kDa forms which are probably variably glycosylated .Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.DNER associates with protein tyrosine phosphatase zeta (PTP zeta ), which is the receptor of pleiotrophin (PTN). PTP zeta -PTN-DNER signaling has been implicated in the regulation of neuritogenesis. Expression of DNER in glioblastoma stem-like cells inhibits formation of neurospheres in vitro, while in vivo it induces differentiation and inhibits growth of xenografts, thus acting as a tumor suppressor.,DNER,UNQ26,bet,Neuroscience,Stem Cells,DNER
    分子量
    78kDa
    基因ID
    92737
    UniProt
    Q8NFT8
    途径
    Skeletal Muscle Fiber Development
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