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CSTB 抗体

CSTB 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266617
发货至: 中国
  • 抗原 See all CSTB 抗体
    CSTB (Cystatin B (Stefin B) (CSTB))
    适用
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    宿主
    • 88
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    克隆类型
    • 90
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    单克隆
    标记
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    This CSTB antibody is un-conjugated
    应用范围
    • 68
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    Western Blotting (WB)
    原理
    Cystatin B Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of Human Cystatin B.
    亚型
    IgG
    Top Product
    Discover our top product CSTB Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CSTB (Cystatin B (Stefin B) (CSTB))
    别名
    Cystatin B (CSTB 产品)
    别名
    CST6 antibody, EPM1 antibody, EPM1A antibody, PME antibody, STFB antibody, ULD antibody, CSTB antibody, Cyb antibody, Epm1 antibody, Stfb antibody, MGC189005 antibody, pme antibody, cst6 antibody, epm1 antibody, stfb antibody, AA960480 antibody, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6 antibody, ATCYS6 antibody, ATCYSB antibody, cystatin B antibody, LOC100008600 antibody, LOC100136235 antibody, CPI1 antibody, cystatin B antibody, cystatin B (stefin B) antibody, cystatin 14a, tandem duplicate 2 antibody, cystatin-B antibody, CSTB antibody, Cstb antibody, cstb antibody, cst14a.2 antibody, CYSB antibody, cpi1 antibody, LOC101123265 antibody
    背景
    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.,CSTB,CPI-B,CST6,EPM1,EPM1A,PME,STFB,ULD,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Ubiquitin,Cystatin B
    分子量
    11kDa
    基因ID
    1476
    UniProt
    P04080
    途径
    Response to Water Deprivation
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