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DMP1 抗体 (AA 561-760)

DMTF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7266560
发货至: 中国
  • 抗原 See all DMP1 (DMTF1) 抗体
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    抗原表位
    • 15
    • 15
    • 10
    • 10
    • 8
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 561-760
    适用
    • 90
    • 19
    • 19
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    宿主
    • 79
    • 8
    • 3
    • 1
    克隆类型
    • 84
    • 7
    多克隆
    标记
    • 35
    • 8
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DMP1 antibody is un-conjugated
    应用范围
    • 65
    • 43
    • 26
    • 26
    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    DMTF1 Rabbit pAb
    序列
    VTVQCHTPRV IIQTVATEDI TSSISQAELT VDSDIQSSDF PEPPDALEAD TFPDEIHHPK MTVEPSFNDA HVSKFSDQNS TELMNSVMVR TEEEISDTDL KQEESPSDLA SAYVTEGLES PTIEEQVDQT IDDETILIVP SPHGFIQASD VIDTESVLPL TTLTDPILQH HQEESNIIGS SLGSPVSEDS KDVEDLVNCH
    交叉反应
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 561-760 of human DMTF1 (NP_066968.3).
    亚型
    IgG
    Top Product
    Discover our top product DMTF1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    别名
    DMTF1 (DMTF1 产品)
    别名
    DMP1 antibody, DMTF antibody, hDMP1 antibody, Dimp antibody, Dmp1 antibody, DMTF1 antibody, zgc:92448 antibody, cyclin D binding myb like transcription factor 1 antibody, cyclin D binding myb-like transcription factor 1 antibody, DMTF1 antibody, Dmtf1 antibody, dmtf1 antibody
    背景
    This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.,DMTF1,DMP1,DMTF,MRUL,hDMP1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cyclins,DMTF1
    基因ID
    9988
    UniProt
    Q9Y222
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