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CD35 抗体

CR1 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266477
发货至: 中国
  • 抗原 See all CD35 (CR1) 抗体
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    适用
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    宿主
    • 65
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    克隆类型
    • 69
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    单克隆
    标记
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    This CD35 antibody is un-conjugated
    应用范围
    • 63
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    Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    CD35/CR1 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human CD35/CR1
    亚型
    IgG
    Top Product
    Discover our top product CR1 Primary Antibody
  • 应用备注
    IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    别名
    CR1 (CR1 产品)
    别名
    C3BR antibody, C4BR antibody, CD35 antibody, KN antibody, C3DR antibody, CD21 antibody, Cr-1 antibody, Cr-2 antibody, Cr1 antibody, CR1-L antibody, CR2 antibody, CR1 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, complement receptor 2 antibody, complement component (3d/Epstein Barr virus) receptor 2 antibody, complement receptor type 1 antibody, CR1 antibody, Cr2 antibody, CR2 antibody, LOC718120 antibody
    背景
    This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq, Jul 2008],C3BR, C4BR, CD35, KN,CDs,Hematopoietic Progenitors,Immunology & Inflammation,Stem Cells,CR1
    分子量
    280kDa
    基因ID
    1378
    UniProt
    P17927
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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