CHM 抗体
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- 抗原 See all CHM 抗体
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CHM antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- CHM Rabbit mAb
- 交叉反应
- 人
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human CHM.
- 亚型
- IgG
- Top Product
- Discover our top product CHM Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
- 别名
- CHM (CHM 产品)
- 别名
- CHM antibody, REP1 antibody, DXS540 antibody, GGTA antibody, HSD-32 antibody, REP-1 antibody, TCD antibody, DKFZp459K2154 antibody, tcd antibody, ggta antibody, rep-1 antibody, dxs540 antibody, hsd-32 antibody, MGC68578 antibody, Rep-1 antibody, chm antibody, chm-a antibody, chm-b antibody, chml antibody, CHM, Rab escort protein 1 antibody, choroideremia (Rab escort protein 1) antibody, choroideremia (Rab escort protein 1) L homeolog antibody, choroidermia (RAB escort protein 1) antibody, choroideremia (Rab escort protein 1) S homeolog antibody, CHM antibody, chm antibody, chm.L antibody, Chm antibody, chm.S antibody
- 背景
- This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.,CHM, DXS540, GGTA, HSD-32, REP-1, TCD, CHM, Rab escort protein 1,Signal Transduction,Neuroscience,CHM
- 分子量
- 95kDa
- 基因ID
- 1121
- UniProt
- P24386
- 途径
- Sensory Perception of Sound
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