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CMKLR1 抗体 (AA 250-350)

CMKLR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7266326
发货至: 中国
  • 抗原 See all CMKLR1 抗体
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    抗原表位
    • 16
    • 15
    • 14
    • 12
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-350
    适用
    • 74
    • 41
    • 24
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 75
    • 3
    • 2
    克隆类型
    • 74
    • 5
    • 1
    多克隆
    标记
    • 30
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CMKLR1 antibody is un-conjugated
    应用范围
    • 60
    • 27
    • 26
    • 26
    • 19
    • 13
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    CMKLR1 Rabbit pAb
    序列
    NRLAKTKKPF KIIVTIIITF FLCWCPYHTL NLLELHHTAM PGSVFSLGLP LATALAIANS CMNPILYVFM GQDFKKFKVA LFSRLVNALS EDTGHSSYPS H
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CMKLR1 (NP_001135815.1).
    亚型
    IgG
    Top Product
    Discover our top product CMKLR1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    别名
    CMKLR1 (CMKLR1 产品)
    别名
    CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
    背景
    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i/G(o and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2, TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis PubMed:27716822. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2 and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism.,CMKLR1,CHEMERINR,ChemR23,DEZ,RVER1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,CMKLR1
    分子量
    42kDa
    基因ID
    1240
    UniProt
    Q99788
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