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PD-L1 抗体 (Extracellular Domain)

PD-L1 适用: 人 IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266181
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    抗原表位
    • 29
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    Extracellular Domain
    适用
    • 165
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    宿主
    • 130
    • 54
    • 19
    • 4
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    • 1
    克隆类型
    • 113
    • 95
    • 2
    单克隆
    标记
    • 91
    • 15
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    • 8
    • 5
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    This PD-L1 antibody is un-conjugated
    应用范围
    • 135
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    • 40
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    • 28
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    Immunohistochemistry (IHC)
    原理
    PD-L1/CD274 Rabbit mAb
    交叉反应
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human PD-L1 extracellular domain.
    亚型
    IgG
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % thimerosal,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    PD-L1 (PD-L1 产品)
    别名
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    背景
    This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.,B7-H,B7H1,PDL1,PD-L1,PDCD1L1,PDCD1LG1,CD274,Immunology & Inflammation,CD markers,PD-L1
    分子量
    20kDa/33kDa
    基因ID
    29126
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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