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CTNNB1 抗体

KO Validated CTNNB1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266138
发货至: 中国
  • 抗原 See all CTNNB1 抗体
    CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
    适用
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    宿主
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    克隆类型
    • 146
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    单克隆
    标记
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    This CTNNB1 antibody is un-conjugated
    应用范围
    • 197
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    原理
    [KO Validated] β-Catenin Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    质量等级
    KO Validated
    免疫原
    A synthesized peptide derived from human beta Catenin.
    亚型
    IgG
    Top Product
    Discover our top product CTNNB1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
    别名
    CTNNB1 (CTNNB1 产品)
    别名
    Jup antibody, LOC100217813 antibody, CTNNB1 antibody, CTNNB antibody, Bfc antibody, Catnb antibody, Mesc antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, ctnnb1 antibody, CHBCAT antibody, MRD19 antibody, armadillo antibody, beta-catenin antibody, catenin beta 1 antibody, catenin (cadherin associated protein), beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 S homeolog antibody, catenin beta 1 L homeolog antibody, CTNNB1 antibody, Ctnnb1 antibody, ctnnb1 antibody, ctnnb1.S antibody, ctnnb1.L antibody
    背景
    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],CTNNB,MRD19,armadillo,beta Catenin,CTNNB1,Angiogenesis,Apoptosis,Cancer,Cardiovascular,Cell Adhesion,Cell Adhesion_Cadherins,Cell Adhesion_Tight Junctions,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Invasion and Metastasis,Neuroscience,Protein phosphorylation,Signal Transduction,Stem Cells,Transcription Factors,Wnt/β-Catenin Signaling Pathway,CTNNB1
    分子量
    92kDa
    基因ID
    1499
    UniProt
    P35222
    途径
    WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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