cradd antibody, MGC89035 antibody, zgc:101717 antibody, CRADD antibody, DKFZp468A2219 antibody, LOC100226369 antibody, raidd antibody, MGC78788 antibody, MRT34 antibody, RAIDD antibody, CASP2 and RIPK1 domain containing adaptor with death domain antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 1 antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog antibody, CRADD antibody, cradd.1 antibody, cradd antibody, cradd.2.S antibody, Cradd antibody
背景
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],MRT34, RAIDD,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Invasion and Metastasis,CRADD