A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Casein Kinase 1 alpha (Casein Kinase 1 alpha (CSNK1A1)) (NP_001020276.1).
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration.,CSNK1A1,CK1,CK1a,CKIa,HEL-S-77p,HLCDGP1,PRO2975,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Stem Cells,CSNK1A1