ABC41 antibody, EST352188 antibody, MAHCJ antibody, P70R antibody, P79R antibody, PMP69 antibody, PXMP1L antibody, Pxmp1l antibody, ABCD4 antibody, zgc:153503 antibody, P69r antibody, ATP binding cassette subfamily D member 4 antibody, ATP-binding cassette, sub-family D (ALD), member 4 antibody, ABCD4 antibody, Abcd4 antibody, abcd4 antibody
背景
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008],ABC41,EST352188,MAHCJ,P70R,P79R,PMP69,PXMP1L,ABCD4,ABCD4