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alpha 2 Macroglobulin 抗体

A2M 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7265558
发货至: 中国
  • 抗原 See all alpha 2 Macroglobulin (A2M) 抗体
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    适用
    • 99
    • 22
    • 19
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    • 3
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    • 1
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    • 1
    宿主
    • 94
    • 19
    • 17
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    克隆类型
    • 110
    • 24
    单克隆
    标记
    • 77
    • 19
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    • 4
    • 2
    • 2
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    This alpha 2 Macroglobulin antibody is un-conjugated
    应用范围
    • 80
    • 49
    • 37
    • 19
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    Alpha-2-Macroglobulin (A2M) Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M))
    亚型
    IgG
    Top Product
    Discover our top product A2M Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    别名
    A2M (A2M 产品)
    背景
    The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016],A2MD, CPAMD5, FWP007, S863-7,Blood,Blood_Serum Proteins,Cardiovascular,Cell Biology & Developmental Biology,Ubiquitin,A2M
    分子量
    163kDa
    基因ID
    2
    UniProt
    P01023
    途径
    Lipid Metabolism
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