AKT 1/2/3 抗体
Quick Overview for AKT 1/2/3 抗体 (ABIN7265520)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Pan-Akt Rabbit pAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide of human AKT1/AKT2/AKT3
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亚型
- IgG
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anti-AKT 1/2/3 (AA 401-479) antibody
适用: 人, 小鼠, 大鼠, Cow, Pig WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT 1/2/3 (pSer473) antibody适用: 人, 小鼠, 大鼠, Cow, 兔, 小鸡, 鱼 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT 1/2/3 (pSer472) antibody适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT 1/2/3 antibody适用: 人, 小鼠, 大鼠, Chimpanzee WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 14E5-16C8-25F6 unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibody适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr474) antibody适用: 人, 小鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibody适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-AKT 1/2/3 (pThr305), (pThr308), (pThr309) antibody适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT 1/2/3 (AA 278-312) antibody适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB43841 unconjugated
anti-AKT 1/2/3 (AA 431-480) antibody适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100,IP,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- AKT 1/2/3
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别名
- AKT1/AKT2/AKT3
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背景
- Human AKT serine-threonine protein kinase family includes three members AKT1,AKT2, AKT3, which are also often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT proteins all have an N-terminal pleckstrin homology domain, a serine/threonine-specific kinase domain and a C-terminal regulatory domain. These proteins are phosphorylated by phosphoinositide 3-kinase (PI3K). AKT/PI3K forms a key component of many signalling pathways that involve the binding of membrane-bound ligands such as receptor tyrosine kinases, G-protein coupled receptors, and integrin-linked kinase. These AKT proteins therefore regulate a wide variety of cellular functions including cell proliferation, survival, metabolism, and angiogenesis in both normal and malignant cells. AKT proteins are recruited to the cell membrane by phosphatidylinositol 3,4,5-trisphosphate (PIP3) after phosphorylation of phosphatidylinositol 4,5-bisphosphate (PIP2) by PI3K. Subsequent phosphorylation of both threonine residue 308 and serine residue 473 is required for full activation of the AKT1 protein encoded by this gene.,AKT1/AKT2/AKT3,Protein phosphorylation,AKT1/AKT2/AKT3
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分子量
- 48kDa/55kDa/51kDa/54kDa
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基因ID
- 207, 208, 10000
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UniProt
- P31749, P31751, Q9Y243
抗原
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