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alpha Actinin 4 抗体

ACTN4 适用: 人 WB, IP, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7265399
发货至: 中国
  • 抗原 See all alpha Actinin 4 (ACTN4) 抗体
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    适用
    • 91
    • 50
    • 46
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 84
    • 7
    克隆类型
    • 73
    • 17
    单克隆
    标记
    • 55
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This alpha Actinin 4 antibody is un-conjugated
    应用范围
    • 68
    • 31
    • 26
    • 16
    • 16
    • 15
    • 13
    • 12
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
    原理
    α-Actinin-4 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human alpha-Actinin-4
    亚型
    IgG
    Top Product
    Discover our top product ACTN4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    别名
    ACTN4 (ACTN4 产品)
    别名
    fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody
    背景
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008],ACTININ-4, FSGS, FSGS1,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Extracellular Matrix,Immunology & Inflammation,Invasion and Metastasis,RNA Binding,Signal Transduction,T Cell Receptor Signaling Pathway,ACTN4
    分子量
    105kDa
    基因ID
    81
    UniProt
    O43707
    途径
    Proton Transport
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