APRIL antibody, PHAPI2 antibody, SSP29 antibody, 2410015B15Rik antibody, PAL31 antibody, PHAPI2a antibody, Ssp29 antibody, cb908 antibody, fa99a11 antibody, wu:fa28c10 antibody, wu:fa99a11 antibody, wu:fb40e12 antibody, zgc:77745 antibody, hLAMP-1 antibody, MGC80871 antibody, ANP32B antibody, MGC69373 antibody, SLAN antibody, acidic nuclear phosphoprotein 32 family member B antibody, acidic (leucine-rich) nuclear phosphoprotein 32 family, member B antibody, acidic nuclear phosphoprotein 32 family member B L homeolog antibody, acidic leucine-rich nuclear phosphoprotein 32 family member B antibody, ANP32B antibody, Anp32b antibody, anp32b antibody, anp32b.L antibody, LOC494442 antibody
背景
Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription. Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis. Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes. Plays also an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1. Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity.,APRIL, PHAPI2, SSP29,Apoptosis,Apoptosis_Caspases,Cell Biology & Developmental Biology,Cell Cycle,ANP32B