This antibody recognizes human, mouse, and rat PCDHG-A, B, and C proteins
交叉反应
人, 小鼠, 大鼠
免疫原
Fusion protein corresponding to aa 808-931 (C-terminal cytoplasmic constant domain) of mouse PCDHGA1. This sequence is present in all 22 PCDHG proteins.
Immunoblotting: use at 1-2 μg/mL. A band of ~100 kDa is detected. Immunofluorescence: use at 10 μg/mL. These are recommended concentrations. Endusers should determine optimal concentrations for their application.
限制
仅限研究用
状态
Liquid
溶解方式
Dilute in PBS or medium that is identical to that used in the assay system.
浓度
1.0 mg/mL
缓冲液
PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
This product is stable for at least one (1) year at -20°C.
Protocadherin γ A1,The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. The gamma gene cluster includes 22 genes divided into 3 subfamilies: subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region (which includes 6 cadherin ectodomains and a trans-membrane region). The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins are believed to play a critical role in the establishment and function of specific cell-cell connections in the brain.