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TGFB1 抗体

TGFB1 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 10E5 unconjugated
产品编号 ABIN7212208
发货至: 中国
  • 抗原 See all TGFB1 抗体
    TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 194
    • 41
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    小鼠
    克隆类型
    • 198
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    单克隆
    标记
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    This TGFB1 antibody is un-conjugated
    应用范围
    • 176
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    TGFβ1 Mouse Monoclonal Antibody (10E5)
    特异性
    TGFβ1 protein detects endogenous levels of TGFB1.
    纯化方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
    免疫原
    Synthetic Peptide of TGFbeta1 at AA range of 310-390
    克隆位点
    10E5
    亚型
    IgG1
    Top Product
    Discover our top product TGFB1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
    说明

    Primary Antibody

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
    别名
    TGFbeta1 (TGFB1 产品)
    别名
    CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta5 antibody, ced antibody, dpd1 antibody, lap antibody, tgf-beta antibody, tgfb antibody, tgfb5 antibody, tgfbeta antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, ai39657 antibody, tgfb1 antibody, wu:fb13a07 antibody, xx:ai39657 antibody, TGFB1 antibody, csd antibody, cdb1 antibody, cdg2 antibody, csd1 antibody, csd2 antibody, csd3 antibody, ebmd antibody, lcd1 antibody, bigh3 antibody, cdgg1 antibody, betaig-h3 antibody, TGFB4 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor beta 1 L homeolog antibody, transforming growth factor, beta 1 antibody, transforming growth factor, beta 1a antibody, transforming growth factor beta induced L homeolog antibody, TGFB1 antibody, Tgfb1 antibody, tgfb1.L antibody, tgfb1a antibody, tgfbi.L antibody
    背景
    Mouse Anti-TGFβ1 Mouse Monoclonal Antibody (10E5),TGFB1,TGFB1 (transforming growth factor beta 1) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. TGFB1 is frequently upregulated in tumor cells, and mutations in TGFB1 result in Camurati-Engelmann disease.,TGFB1
    分子量
    observerd band 12,25,45-65kDa
    基因ID
    7040
    UniProt
    P01137
    途径
    EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
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