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SREBF1 抗体

SREBF1 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7217110
发货至: 中国
  • 抗原 See all SREBF1 抗体
    SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
    适用
    • 66
    • 29
    • 24
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 64
    • 7
    克隆类型
    • 63
    • 7
    多克隆
    标记
    • 46
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This SREBF1 antibody is un-conjugated
    应用范围
    • 50
    • 32
    • 15
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    SREBP-1 Polyclonal Antibody
    特异性
    SREBP-1 Polyclonal Antibody detects endogenous levels of SREBP-1 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    免疫原
    Synthesized peptide derived from human SREBP-1 around the non-phosphorylation site of S439
    亚型
    IgG
    Top Product
    Discover our top product SREBF1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
    说明

    Primary Antibody

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
    别名
    SREBP-1 (SREBF1 产品)
    别名
    SREBP-1c antibody, SREBP1 antibody, bHLHd1 antibody, ADD-1 antibody, ADD1 antibody, D630008H06 antibody, SREBP-1 antibody, SREBP-1a antibody, SREBP1c antibody, Srebp1 antibody, SCREBP1 antibody, SREBP-1C antibody, SREBF1 antibody, srebp1 antibody, sterol regulatory element binding transcription factor 1 antibody, sterol regulatory element binding transcription factor 1 L homeolog antibody, sterol regulatory element binding protein-1 antibody, Sterol regulatory element Binding Protein antibody, SREBF1 antibody, Srebf1 antibody, srebf1.L antibody, SREBP-1 antibody, srebf1 antibody, sbp-1 antibody
    背景
    Rabbit Anti-SREBP-1 Polyclonal Antibody,SREBF1, BHLHD1, SREBP1, Sterol regulatory element-binding protein 1, SREBP-1, Class D basic helix-loop-helix protein 1, bHLHd1, Sterol regulatory element-binding transcription factor 1,SREBF1 encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element-binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17.,Sterol regulatory element-binding protein 1
    分子量
    observerd band 122kDa
    基因ID
    6720
    UniProt
    P36956
    途径
    AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
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