OPN4 抗体 (AA 400-480)
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- 抗原 See all OPN4 抗体
- OPN4 (Opsin 4 (OPN4))
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抗原表位
- AA 400-480
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OPN4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 原理
- Melanopsin Polyclonal Antibody
- 特异性
- Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 免疫原
- Synthesized peptide derived from the C-terminal region of human Melanopsin at AA range: 400-480
- 亚型
- IgG
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
- 说明
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Primary Antibody
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- 抗原
- OPN4 (Opsin 4 (OPN4))
- 别名
- Melanopsin (OPN4 产品)
- 别名
- MOP antibody, 1110007J02Rik antibody, Gm533 antibody, OPN4-2 antibody, cOpn4L antibody, melanopsin antibody, opn4-A antibody, Xmop antibody, opn4 antibody, opn4d antibody, opsin 4 antibody, opsin 4 (melanopsin) antibody, melanopsin antibody, melanopsin-B-like L homeolog antibody, opsin 4a (melanopsin) antibody, OPN4 antibody, Opn4 antibody, LOC100303707 antibody, LOC100485437.L antibody, opn4a antibody
- 背景
- Rabbit Anti-Melanopsin Polyclonal Antibody,OPN4, MOP, Melanopsin, Opsin-4,Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. Melanopsin functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,Melanopsin
- 分子量
- observerd band 55kDa
- 基因ID
- 94233
- UniProt
- Q9UHM6
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