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NRF2 抗体 (acLys599)

NFE2L2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7212658
发货至: 中国
  • 抗原 See all NRF2 (NFE2L2) 抗体
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    抗原表位
    • 21
    • 15
    • 9
    • 9
    • 8
    • 8
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    • 1
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    acLys599
    适用
    • 112
    • 54
    • 53
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 104
    • 10
    • 1
    克隆类型
    • 96
    • 19
    多克隆
    标记
    • 56
    • 10
    • 6
    • 6
    • 4
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This NRF2 antibody is un-conjugated
    应用范围
    • 88
    • 49
    • 24
    • 21
    • 17
    • 15
    • 15
    • 14
    • 12
    • 9
    • 7
    • 2
    • 2
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    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Nrf2 (Acetyl Lys599) Polyclonal Antibody
    特异性
    Acetyl-Nrf2 (K599) Polyclonal Antibody detects endogenous levels of Nrf2 protein only when non-acetylation at K599.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    免疫原
    Synthesized peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599
    亚型
    IgG
    Top Product
    Discover our top product NFE2L2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
    说明

    Primary Antibody

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    别名
    Nrf2 (NFE2L2 产品)
    别名
    Nrf2 antibody, nfe2l2 antibody, wu:fc15g09 antibody, wu:fj67e03 antibody, NF-E2R2 antibody, NRF2 antibody, AI194320 antibody, nuclear factor, erythroid 2-like 2a antibody, nuclear factor, erythroid 2 like 2 S homeolog antibody, nuclear factor, erythroid 2 like 2 antibody, nuclear factor, erythroid derived 2, like 2 antibody, nuclear factor, erythroid 2-like 2 antibody, nfe2l2a antibody, nfe2l2.S antibody, NFE2L2 antibody, Nfe2l2 antibody
    背景
    Rabbit Anti-Nrf2 (Acetyl Lys599) Polyclonal Antibody,NFE2L2, NRF2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2,NFE2L2 encodes a transcription factor (nuclear factor, erythroid 2 like 2) which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for NFE2L2.,Nuclear factor erythroid 2-related factor 2
    分子量
    observerd band 75-100kDa
    基因ID
    4780
    UniProt
    Q16236
    途径
    ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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