Dual Specificity Phosphatase 3 (DUSP3) (AA 41-140) 抗体
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- 抗原 See all Dual Specificity Phosphatase 3 (DUSP3) 抗体
- Dual Specificity Phosphatase 3 (DUSP3)
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抗原表位
- AA 41-140
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DUSP3
- 亚型
- IgG
- Top Product
- Discover our top product DUSP3 Primary Antibody
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anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibody
DUSP3 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) antibodyDUSP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-30), (N-Term) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06032 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibodyDUSP3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (N-Term) antibodyDUSP3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 157-185), (C-Term) antibodyDUSP3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB5730 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 14-96) antibodyDUSP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Dual Specificity Phosphatase 3 (DUSP3)
- 别名
- Dusp3 (DUSP3 产品)
- 别名
- dusp3 antibody, si:bz18k17.3 antibody, si:rp71-18k17.3 antibody, VHR antibody, RGD1560049 antibody, 2210015O03Rik antibody, 5031436O03Rik antibody, T-DSP11 antibody, dual specificity phosphatase 3 antibody, dual specificity phosphatase 3b antibody, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) antibody, DUSP3 antibody, dusp3b antibody, Dusp3 antibody
- 物质类
- Viral Protein
- 背景
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Synonyms: Dual specicity phosphatase 3, Dual specicity protein phosphatase 3, Dual specicity protein phosphatase VHR, DUS3_HUMAN, DUSP3, Serine/threonine specic protein phosphatase, Vaccinia H1-related phosphatase, Vaccinia virus phosphatase VH1 related, VHR.
Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
- 基因ID
- 1845
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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