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ERK1/2 抗体

MAPK1/3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7206468
发货至: 中国
  • 抗原 See all ERK1/2 (MAPK1/3) 抗体
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    适用
    • 186
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    • 2
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    人, 小鼠, 大鼠
    宿主
    • 138
    • 49
    • 4
    小鼠
    克隆类型
    • 135
    • 56
    单克隆
    标记
    • 90
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    This ERK1/2 antibody is un-conjugated
    应用范围
    • 149
    • 65
    • 51
    • 49
    • 48
    • 38
    • 22
    • 22
    • 20
    • 13
    • 4
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    P44/42 MAPK (ERK1/2) Monoclonal Antibody
    纯化方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
    免疫原
    Synthetic Peptide
    亚型
    IgG1
    Top Product
    Discover our top product MAPK1/3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:50-1:100).
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    别名
    P44/42 MAPK (ERK1/2) (MAPK1/3 产品)
    别名
    erk1/2 antibody, mitogen-activated protein kinase antibody, erk1/2 antibody
    背景
    Mouse Anti-P44/42 MAPK (ERK1/2) Monoclonal Antibody,MAPK3, ERK1, PRKM3, Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p,MAPK1 (mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for MAPK1.,P44
    基因ID
    5594, 5595
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