LAT 抗体
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- 抗原 See all LAT 抗体
- LAT (Linker For Activation of T Cells (LAT))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LAT antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- LAT Polyclonal Antibody
- 特异性
- LAT Polyclonal Antibody detects endogenous levels of LAT protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 免疫原
- Synthesized peptide derived from human LAT around the non-phosphorylation site of Y200
- 亚型
- IgG
- Top Product
- Discover our top product LAT Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
- 说明
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Primary Antibody
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- 抗原
- LAT (Linker For Activation of T Cells (LAT))
- 别名
- LAT (LAT 产品)
- 别名
- LAT antibody, lat antibody, LAT1 antibody, pp36 antibody, linker for activation of T-cells antibody, linker for activation of T cells antibody, LAT antibody, lat antibody, Lat antibody
- 背景
- Rabbit Anti-LAT Polyclonal Antibody,LAT, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38,Linker for activation of T-cells family member 1 encoded by LAT is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.,Linker for activation of T-cells family member 1
- 分子量
- observerd band 38kDa
- 基因ID
- 27040
- UniProt
- O43561
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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