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IL4 Receptor 抗体

IL4R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7215426
发货至: 中国
  • 抗原 See all IL4 Receptor (IL4R) 抗体
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    适用
    • 62
    • 43
    • 22
    人, 小鼠
    宿主
    • 76
    • 9
    • 2
    • 2
    • 1
    克隆类型
    • 81
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    • 1
    多克隆
    标记
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    This IL4 Receptor antibody is un-conjugated
    应用范围
    • 78
    • 26
    • 25
    • 14
    • 14
    • 13
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    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    IL-4Rα Polyclonal Antibody
    特异性
    IL-4Rα Polyclonal Antibody detects endogenous levels of IL-4Rα protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    免疫原
    Synthesized peptide derived from human IL-4Ralpha around the non-phosphorylation site of Y497
    亚型
    IgG
    Top Product
    Discover our top product IL4R Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
    说明

    Primary Antibody

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    别名
    IL-4Ralpha (IL4R 产品)
    别名
    IL4R antibody, il-4ra antibody, zgc:113063 antibody, CD124 antibody, IL-4RA antibody, IL4RA antibody, Il4ra antibody, IL4 antibody, Il4r antibody, interleukin 4 receptor antibody, interleukin 4 receptor, tandem duplicate 1 antibody, interleukin 4 receptor, alpha antibody, IL4R antibody, il4r.1 antibody, Il4r antibody, Il4ra antibody
    背景
    Rabbit Anti-IL-4Rα Polyclonal Antibody,IL4R, IL4RA, 582J2.1, Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD antigen CD124,IL4R encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. Interleukin-4 receptor subunit alpha also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.,Interleukin-4 receptor subunit alpha
    分子量
    observerd band 90kDa
    基因ID
    3566
    UniProt
    P24394
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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