Collagen Type I 抗体
-
- 抗原 See all Collagen Type I (COL1) 抗体
- Collagen Type I (COL1) (Collagen, Type I (COL1))
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Collagen Type I antibody is un-conjugated
-
应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 原理
- Collagen I Mouse Monoclonal Antibody (4H10)
- 特异性
- The antibody detects endogenous Collagen I protein.
- 纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
- 免疫原
- Synthetic Peptide of Collagen I
- 克隆位点
- 4H10
- 亚型
- IgG1
- Top Product
- Discover our top product COL1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200).
- 说明
-
Primary Antibody
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
- 抗原
- Collagen Type I (COL1) (Collagen, Type I (COL1))
- 别名
- Collagen I (COL1 产品)
- 别名
- collagen type III alpha 1 chain antibody, COL3A1 antibody
- 背景
- Mouse Anti-Collagen I Mouse Monoclonal Antibody (4H10),Collagen alpha-1(I) chain, Alpha-1 type I collagen,COL1A1 (collagen type I alpha 1 chain) encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in COL1A1 are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for COL1A1.,Collagen alpha-1(I) chain (Alpha-1 type I collagen)
- 分子量
- observerd band 139kDa
- 基因ID
- 1277, 1278
- UniProt
- P02452
-