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beta Catenin 抗体

CATNB 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7202102
发货至: 中国
  • 抗原 See all beta Catenin (CATNB) 抗体
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 287
    • 56
    • 4
    • 1
    • 1
    小鼠
    克隆类型
    • 280
    • 69
    单克隆
    标记
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    This beta Catenin antibody is un-conjugated
    应用范围
    • 214
    • 159
    • 120
    • 118
    • 80
    • 64
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    • 51
    • 34
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    • 24
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Catenin-β Monoclonal Antibody
    特异性
    The antibody detects endogenous Catenin-β protein.
    纯化方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen
    免疫原
    Recombinant Protein
    亚型
    IgG1
    Top Product
    Discover our top product CATNB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IF (1:100-1:200), IHC-P (1:200-1:500).
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    别名
    Catenin-beta (CATNB 产品)
    别名
    Bfc antibody, Catnb antibody, Mesc antibody, CTNNB antibody, MRD19 antibody, armadillo antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, beta-catenin antibody, ctnnb1 antibody, CHBCAT antibody, catenin (cadherin associated protein), beta 1 antibody, catenin beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 L homeolog antibody, Ctnnb1 antibody, CTNNB1 antibody, ctnnb1 antibody, ctnnb1.L antibody
    背景
    Mouse Anti-Catenin-β Monoclonal Antibody,The protein encoded by CTNNB1 (catenin beta 1) is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.,Catenin beta-1
    基因ID
    1499
    UniProt
    P35222
    途径
    Peptide Hormone Metabolism
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