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NCKAP1 抗体 (AA 1001-1132) (Cy3)

NCKAP1 适用: 小鼠 WB 宿主: 兔 Polyclonal Cy3
产品编号 ABIN715739
发货至: 中国
  • 抗原 See all NCKAP1 抗体
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1001-1132
    适用
    • 33
    • 26
    • 11
    小鼠
    宿主
    • 46
    • 1
    克隆类型
    • 47
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCKAP1 antibody is conjugated to Cy3
    应用范围
    • 36
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NCKAP1L
    亚型
    IgG
    Top Product
    Discover our top product NCKAP1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    别名
    NCKAP1 (NCKAP1 产品)
    别名
    HEM2 antibody, NAP1 antibody, NAP125 antibody, p125Nap1 antibody, C79304 antibody, H19 antibody, Hem-2 antibody, Hem2 antibody, Nap1 antibody, mKIAA0587 antibody, mh19 antibody, NCK associated protein 1 antibody, NCK-associated protein 1 antibody, NCK-associated protein 1 L homeolog antibody, NCKAP1 antibody, Nckap1 antibody, nckap1.L antibody
    背景

    Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.

    Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

    基因ID
    10787
    UniProt
    P55160
    途径
    RTK signaling, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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