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Recombinant EGFR (Panitumumab Biosimilar) 抗体

适用: 人 FACS, in vivo 宿主: 小鼠 Monoclonal unconjugated Recombinant Antibody
产品编号 ABIN7200662
发货至: 中国
  • 抗原 See all EGFR (Panitumumab Biosimilar) products
    EGFR (Panitumumab Biosimilar)
    抗体类型
    Recombinant Antibody
    适用
    宿主
    • 1
    小鼠
    克隆类型
    • 1
    单克隆
    标记
    • 1
    This EGFR (Panitumumab Biosimilar) antibody is un-conjugated
    应用范围
    Flow Cytometry (FACS), In vivo Studies (in vivo)
    原理
    Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody
    特异性
    The monoclonal antibody panitumumab biosimilar specifically binds to the human EGFR, ErbB-1 and HER1.
    产品特性
    Recombinant Humanized IgG2 Monoclonal Antibody.
    纯化方法
    Protein A affinity column
    纯度
    > 95% by SDS-PAGE under reducing conditions and HPLC.
    过滤
    0.2 μm filtered
    内毒素水平
    < 1 EU per 1 mg of the protein by the LAL method.
    免疫原
    The monoclonal antibody panitumumab biosimilar was produced in the Panitumumab biosimilar CHO stable cell line.
    亚型
    IgG2 kappa
  • 应用备注
    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by panitumumab.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.4, no stabilizers or preservatives.
    储存液
    Without preservative
    注意事项
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
    有效期
    12 months
  • 抗原
    EGFR (Panitumumab Biosimilar)
    Abstract
    EGFR (Panitumumab Biosimilar) 产品
    物质类
    Biosimilar
    背景
    Panitumumab, a fully anti-EGFR (epidermal growth factor receptor, EGF receptor, ErbB-1 and HER1 in humans) human monoclonal antibody, is used for the treatment of refractory EGFR-expressing metastatic colorectal cancer in patients with non-mutated (wild-type) KRAS".
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