Recombinant EGFR (Panitumumab Biosimilar) 抗体
适用: 人
FACS, in vivo
宿主: 小鼠
Monoclonal
unconjugated
Recombinant Antibody
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- 抗原 See all EGFR (Panitumumab Biosimilar) products
- EGFR (Panitumumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This EGFR (Panitumumab Biosimilar) antibody is un-conjugated
- 应用范围
- Flow Cytometry (FACS), In vivo Studies (in vivo)
- 原理
- Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody
- 特异性
- The monoclonal antibody panitumumab biosimilar specifically binds to the human EGFR, ErbB-1 and HER1.
- 产品特性
- Recombinant Humanized IgG2 Monoclonal Antibody.
- 纯化方法
- Protein A affinity column
- 纯度
- > 95% by SDS-PAGE under reducing conditions and HPLC.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method.
- 免疫原
- The monoclonal antibody panitumumab biosimilar was produced in the Panitumumab biosimilar CHO stable cell line.
- 亚型
- IgG2 kappa
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- 应用备注
- ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by panitumumab.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4, no stabilizers or preservatives.
- 储存液
- Without preservative
- 注意事项
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
- 有效期
- 12 months
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- 抗原
- EGFR (Panitumumab Biosimilar)
- Abstract
- EGFR (Panitumumab Biosimilar) 产品
- 物质类
- Biosimilar
- 背景
- Panitumumab, a fully anti-EGFR (epidermal growth factor receptor, EGF receptor, ErbB-1 and HER1 in humans) human monoclonal antibody, is used for the treatment of refractory EGFR-expressing metastatic colorectal cancer in patients with non-mutated (wild-type) KRAS".
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