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Recombinant VEGF (Bevacizumab Biosimilar) 抗体

适用: 人 FACS, in vivo 宿主: 小鼠 Monoclonal unconjugated Recombinant Antibody
产品编号 ABIN7200653
发货至: 中国
  • 抗原 See all VEGF (Bevacizumab Biosimilar) products
    VEGF (Bevacizumab Biosimilar)
    抗体类型
    Recombinant Antibody
    适用
    宿主
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 3
    • 2
    单克隆
    标记
    • 5
    This VEGF (Bevacizumab Biosimilar) antibody is un-conjugated
    应用范围
    • 4
    • 3
    • 3
    • 3
    • 3
    Flow Cytometry (FACS), In vivo Studies (in vivo)
    原理
    Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody
    特异性
    The monoclonal antibody Bevacizumab biosimilar specifically binds to the human VEGF-A.
    产品特性
    Recombinant Humanized IgG1 Monoclonal Antibody generated from the same parent mouse antibody as ranibizumab.
    纯化方法
    Protein A affinity column
    纯度
    > 95% by SDS-PAGE under reducing conditions and HPLC.
    过滤
    0.2 μm filtered
    内毒素水平
    < 1 EU per 1 mg of the protein by the LAL method.
    免疫原
    The monoclonal antibody Bevacizumab biosimilar was produced in the bevacizumab biosimilar CHO stable cell line.
    亚型
    IgG1 kappa
  • 应用备注
    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.4, no stabilizers or preservatives.
    储存液
    Without preservative
    注意事项
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
    有效期
    12 months
  • 抗原
    VEGF (Bevacizumab Biosimilar)
    Abstract
    VEGF (Bevacizumab Biosimilar) 产品
    别名
    MVCD1 antibody, VEGF antibody, VPF antibody, vascular endothelial growth factor A antibody, VEGFA antibody
    物质类
    Biosimilar
    背景
    Bevacizumab, the humanized anti-VEGF-A monoclonal antibody, produces angiogenesis inhibition and slows the growth of new blood vessels. As the first clinically available angiogenesis inhibitor in the United States, Bevacizumab is used for treatment of certain metastatic cancers, certain lung cancers, renal cancers, ovarian cancers, breast cancers, and glioblastoma multiforme of the brain.

    Vascular endothelial growth factor A (VEGF-A) stimulates angiogenesis in a variety of cancers, including colorectal, lung, breast, glioblastoma, kidney, and ovarian cancers.
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