RAB8A 抗体 (AA 101-207)
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- 抗原 See all RAB8A 抗体
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
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抗原表位
- AA 101-207
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAB8A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Sheep,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RAB8A
- 亚型
- IgG
- Top Product
- Discover our top product RAB8A Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
- 别名
- Rab8 (RAB8A 产品)
- 别名
- rab8A antibody, DDBDRAFT_0206521 antibody, DDBDRAFT_0214885 antibody, DDB_0206521 antibody, DDB_0214885 antibody, HSH2D antibody, mel antibody, rab8 antibody, c-mel antibody, MEL antibody, RAB8 antibody, zgc:162699 antibody, AA409338 antibody, Mel antibody, Rab8 antibody, rab8A protein antibody, Rab GTPase antibody, RAB8A, member RAS oncogene family antibody, RAB8A, member RAS oncogene family S homeolog antibody, rab8A antibody, RAB8A antibody, rab8a antibody, rab8a.S antibody, Rab8a antibody
- 背景
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Synonyms: MEL, RAB8, Ras-related protein Rab-8A, Oncogene c-mel, RAB8A
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization. Plays an important role in ciliogenesis. Together with MICALL2, may also regulate adherens junction assembly. May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis.
- 基因ID
- 4218
- UniProt
- P61006
- 途径
- M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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