IL-1 beta 抗体 (AA 117-269)
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- 抗原 See all IL-1 beta (IL1B) 抗体
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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抗原表位
- AA 117-269
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL-1 beta antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- IL1B Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human IL1B (AA: 117-269) expressed in E. Coli.
- 克隆位点
- 5C3B7
- 亚型
- IgG1
- Top Product
- Discover our top product IL1B Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- 别名
- IL1B (IL1B 产品)
- 别名
- IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
- 背景
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Description:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase2 by this cytokine in the central nervous system is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Aliases: IL-1, IL1F2, IL1beta, IL1-BETA
- 分子量
- 30.7kDa
- 基因ID
- 3553
- 途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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