HLA-F 抗体 (AA 22-305)
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- 抗原 See all HLA-F (HLAF) 抗体
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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抗原表位
- AA 22-305
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-F antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. coli.
- 克隆位点
- 3F11F4
- 亚型
- IgG2b
- Top Product
- Discover our top product HLAF Primary Antibody
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- 应用备注
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- 限制
- 仅限研究用
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- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
- 别名
- HLA-F (HLAF 产品)
- 别名
- HLAF antibody, CDA12 antibody, HLA-5.4 antibody, HLA-CDA12 antibody, major histocompatibility complex, class I, F antibody, HLA-F antibody
- 背景
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Description: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.
Aliases: HLAF, CDA12, HLA-5.4, HLA-CDA12
- 分子量
- 39 kDa
- 基因ID
- 3134
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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