CXCR6 抗体
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- 抗原 See all CXCR6 抗体
- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CXCR6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- CD186 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD186 expressed in E. Coli.
- 克隆位点
- 2A4D10
- 亚型
- IgG1
- Top Product
- Discover our top product CXCR6 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
- 别名
- CD186 (CXCR6 产品)
- 别名
- BONZO antibody, CD186 antibody, STRL33 antibody, TYMSTR antibody, BB217514 antibody, C-X-C motif chemokine receptor 6 antibody, chemokine (C-X-C motif) receptor 6 L homeolog antibody, chemokine (C-X-C motif) receptor 6 antibody, CXCR6 antibody, cxcr6.L antibody, Cxcr6 antibody
- 背景
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Description:
The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4.
Aliases: CXCR6, BONZO, CDw186, STRL33, TYMSTR
- 分子量
- 39.3kDa
- 基因ID
- 10663
- UniProt
- O00574
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