SIGLEC8 抗体 (AA 17-216)
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- 抗原 See all SIGLEC8 抗体
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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抗原表位
- AA 17-216
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SIGLEC8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- SIGLEC8 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human SIGLEC8 (AA: 17-216) expressed in E. Coli.
- 克隆位点
- 1A5B9
- 亚型
- IgG2b
- Top Product
- Discover our top product SIGLEC8 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- 别名
- SIGLEC8 (SIGLEC8 产品)
- 别名
- SAF2 antibody, SIGLEC-8 antibody, SIGLEC8L antibody, SIGLEC8 antibody, sialic acid binding Ig like lectin 8 antibody, sialic acid-binding Ig-like lectin 8 antibody, SIGLEC8 antibody, LOC506364 antibody
- 背景
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Description:
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983])
Aliases: SAF2, SIGLEC-8, SIGLEC8L
- 分子量
- 54kDa
- 基因ID
- 27181
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