GZMB 抗体 (AA 21-247)
-
- 抗原 See all GZMB 抗体
- GZMB (Granzyme B (GZMB))
-
抗原表位
- AA 21-247
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This GZMB antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), ELISA
- 原理
- GZMB Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. Coli.
- 克隆位点
- 2G12G7
- 亚型
- IgG2a
- Top Product
- Discover our top product GZMB Primary Antibody
-
-
- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- 抗原
- GZMB (Granzyme B (GZMB))
- 别名
- GZMB (GZMB 产品)
- 别名
- CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
- 背景
-
Description:
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
Aliases: C11, HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1
- 分子量
- 28kDa
- 基因ID
- 3002
- UniProt
- P10144
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
-