DR3/LARD 抗体
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- 抗原 See all DR3/LARD (TNFRSF25) 抗体
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DR3/LARD antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human TNFRSF25 (AA: extra(25-199)) expressed in E. coli.
- 克隆位点
- 4G12H11
- 亚型
- IgG1
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- 应用备注
- WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
- 限制
- 仅限研究用
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- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- 别名
- TNFRSF25 (TNFRSF25 产品)
- 别名
- APO-3 antibody, DDR3 antibody, DR3 antibody, LARD antibody, TNFRSF12 antibody, TR3 antibody, TRAMP antibody, WSL-1 antibody, WSL-LR antibody, Tnfrsf12 antibody, Wsl antibody, TNFRSF25 antibody, TNF receptor superfamily member 25 antibody, tumor necrosis factor receptor superfamily, member 25 antibody, TNFRSF25 antibody, Tnfrsf25 antibody
- 背景
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]
Aliases: DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, GEF720, WSL-LR, PLEKHG5, TNFRSF12
- 分子量
- 45.4 kDa
- 基因ID
- 8718
- 途径
- Apoptosis
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