ACTH 抗体
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- 抗原 See all ACTH 抗体
- ACTH (Adrenocorticotropic hormone (ACTH))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ACTH antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
- 原理
- ACTH Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human ACTH expressed in E. Coli.
- 克隆位点
- 3A4H4
- 亚型
- IgG1
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anti-Adrenocorticotropic hormone (ACTH) antibody
ACTH 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1A9C6 unconjugated
anti-Adrenocorticotropic hormone (ACTH) (AA 18-39) antibodyACTH 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenocorticotropic hormone (ACTH) (AA 1-39) antibodyACTH 适用: 人, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenocorticotropic hormone (ACTH) antibodyACTH 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- ACTH (Adrenocorticotropic hormone (ACTH))
- 别名
- ACTH (ACTH 产品)
- 别名
- ACTH antibody, BE antibody, Beta-LPH antibody, Clip antibody, Gamma-LPH antibody, Npp antibody, Pomc-1 antibody, Pomc1 antibody, alpha-MSH antibody, alphaMSH antibody, beta-MSH antibody, gamma-MSH antibody, CLIP antibody, LPH antibody, MSH antibody, NPP antibody, POC antibody, pro-opiomelanocortin-alpha antibody, proopiomelanocortin antibody, Pomc antibody, POMC antibody
- 背景
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Description:
This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
Aliases: POMC, LPH, MSH, NPP, POC, CLIP
- 分子量
- 29.4kDa
- 基因ID
- 5443
- UniProt
- P01189
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
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