Prosaposin 抗体 (AA 17-216)
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- 抗原 See all Prosaposin (PSAP) 抗体
- Prosaposin (PSAP)
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抗原表位
- AA 17-216
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Prosaposin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- PSAP Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PSAP (AA: 17-216) expressed in E. Coli.
- 克隆位点
- 3B4A8
- 亚型
- IgG1
- Top Product
- Discover our top product PSAP Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- Prosaposin (PSAP)
- 别名
- PSAP (PSAP 产品)
- 别名
- GLBA antibody, SAP1 antibody, AI037048 antibody, SGP-1 antibody, SGP1A antibody, cb759 antibody, wu:fa14a06 antibody, wu:fb36e02 antibody, wu:fb58g07 antibody, PSAP antibody, PSP-A antibody, SFTPA1B antibody, SP-A antibody, prosaposin antibody, surfactant protein A1 antibody, PSAP antibody, Psap antibody, psap antibody, LOC100011417 antibody, LOC100304726 antibody, LOC100526719 antibody, SFTPA1 antibody
- 背景
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Description:
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Aliases: GLBA, SAP1, SAP2
- 分子量
- 58.1kDa
- 基因ID
- 5660
- UniProt
- P07602
- 途径
- Positive Regulation of Endopeptidase Activity
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