WT1 抗体 (AA 1-181)
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- 抗原 See all WT1 抗体
- WT1 (Wilms Tumor 1 (WT1))
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抗原表位
- AA 1-181
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This WT1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 原理
- WT1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human WT1 (AA: 1-181) expressed in E. Coli.
- 克隆位点
- 7F9E8
- 亚型
- IgG1
- Top Product
- Discover our top product WT1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- WT1 (Wilms Tumor 1 (WT1))
- 别名
- WT1 (WT1 产品)
- 别名
- AWT1 antibody, EWS-WT1 antibody, GUD antibody, NPHS4 antibody, WAGR antibody, WIT-2 antibody, WT33 antibody, CWT1 antibody, WT1 antibody, XWT1a antibody, wt-1 antibody, wt1 antibody, xWT1 antibody, WT-1 antibody, gud antibody, wagr antibody, wt33 antibody, xwt1 antibody, wit-2 antibody, si:ch211-160j6.3 antibody, zgc:152697 antibody, D630046I19Rik antibody, Wt-1 antibody, XWT1b antibody, XeWT1 antibody, Wilms tumor 1 antibody, Wilms tumor 1 S homeolog antibody, wilms tumor 1b antibody, Wilms tumor protein antibody, Wilms tumor 1 homolog antibody, Wilms tumor 1 L homeolog antibody, WT1 antibody, wt1.S antibody, wt1 antibody, wt1b antibody, Wt1 antibody, wt1.L antibody
- 背景
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Description:
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
Aliases: GUD, AWT1, WAGR, WT33, NPHS4, WIT-2
- 分子量
- 49.2kDa
- 基因ID
- 7490
- UniProt
- P19544
- 途径
- Tube Formation
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