MYLK 抗体 (AA 1375-1524)
-
- 抗原 See all MYLK 抗体
- MYLK (Myosin Light Chain Kinase (MYLK))
-
抗原表位
- AA 1375-1524
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This MYLK antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- MYLK Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human MYLK (AA:1375-1524) expressed in E. Coli.
- 克隆位点
- 7F2B11
- 亚型
- IgG1
-
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- 抗原
- MYLK (Myosin Light Chain Kinase (MYLK))
- 别名
- MYLK (MYLK 产品)
- 别名
- AAT7 antibody, KRP antibody, MLCK antibody, MLCK1 antibody, MLCK108 antibody, MLCK210 antibody, MSTP083 antibody, MYLK1 antibody, smMLCK antibody, 9530072E15Rik antibody, A930019C19Rik antibody, AW489456 antibody, Mlck antibody, SMMLCK antibody, mlck antibody, fj60a06 antibody, mlck1a antibody, mylk antibody, wu:fj60a06 antibody, zmlck1 antibody, myosin light chain kinase antibody, myosin, light polypeptide kinase antibody, myosin, light chain kinase a antibody, MYLK antibody, Mylk antibody, mylka antibody
- 背景
-
Description:
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.
Aliases: KRP, AAT7, MLCK, MLCK1, MMIHS, MYLK1, s mMLCK, MLCK108, MLCK210, MSTP083
- 分子量
- 210kDa
- 基因ID
- 4638
- UniProt
- Q15746
-