IL4 Receptor 抗体 (AA 26-232)
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- 抗原 See all IL4 Receptor (IL4R) 抗体
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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抗原表位
- AA 26-232
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL4 Receptor antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD124 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD124 (AA: 26-232) expressed in E. Coli.
- 克隆位点
- 4B12B12
- 亚型
- IgG2b
- Top Product
- Discover our top product IL4R Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- 别名
- CD124 (IL4R 产品)
- 别名
- IL4R antibody, il-4ra antibody, zgc:113063 antibody, CD124 antibody, IL-4RA antibody, IL4RA antibody, Il4ra antibody, IL4 antibody, Il4r antibody, interleukin 4 receptor antibody, interleukin 4 receptor, tandem duplicate 1 antibody, interleukin 4 receptor, alpha antibody, IL4R antibody, il4r.1 antibody, Il4r antibody, Il4ra antibody
- 背景
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Description:
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
Aliases: IL4R, IL4RA, IL-4RA
- 分子量
- 89.7kDa
- 基因ID
- 3566
- UniProt
- P24394
- 途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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