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ZAP70 抗体 (AA 169-390)

Name: ZAP70 抗体 (AA 169-390)
Brand: antibodies-online
SKU: ABIN7193547
Availability: OutOfStock

ZAP70 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1F3G9 unconjugated

Western blot analysis using ZAP70 mAb against human ZAP70 (AA: 169-390) recombinant protein. (ZAP70 抗体 (AA 169-390))

Flow cytometric analysis of Jurkat cells using ZAP70 mouse mAb (green) and negative control (red). (ZAP70 抗体 (AA 169-390))

FACS

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (ZAP70 抗体 (AA 169-390))

ELISA

Western blot analysis using ZAP70 mAb against HEK293 (1) and ZAP70 (AA: 169-390)-hIgGFc transfected HEK293 (2) cell lysate. (ZAP70 抗体 (AA 169-390))

Western blot analysis using ZAP70 mouse mAb against MLOT4 (1) cell lysate. (ZAP70 抗体 (AA 169-390))

5 images

产品编号 ABIN7193547

发货至: 中国

Datasheet as PDF

抗原 See all ZAP70 抗体

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
抗原表位
34

33

25

20

17

16

14

10

10

9

8

8

8

7

7

6

6

6

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 169-390
适用
269

126

48

8

7

6

6

5

5

3

3

2

1
人
宿主
205

60

2

2

1
小鼠
Compatible Secondaries
克隆类型
198

71
单克隆
标记
133

16

15

12

11

6

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1
This ZAP70 antibody is un-conjugated
应用范围
192

116

101

65

53

53

44

23

22

22

13

12

6

6

3

2

2

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

原理

ZAP70 Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human ZAP70 (AA: 169-390) expressed in E. Coli.

克隆位点

1F3G9

亚型

IgG1

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ZAP70 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 2F3-2 unconjugated

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ZAP70 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D9C2 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 247-382) antibody
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anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-300) antibody
ZAP70 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr319) antibody
ZAP70 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
抗原

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

别名

ZAP70 (ZAP70 产品)

别名

SRK antibody, STCD antibody, STD antibody, TZK antibody, ZAP-70 antibody, 70kDa antibody, AI327364 antibody, Srk antibody, mrtle antibody, mur antibody, zap70 antibody, MGC80670 antibody, MGC88962 antibody, ZAP70 antibody, zgc:110383 antibody, zeta chain of T-cell receptor associated protein kinase 70 antibody, putative tyrosine-protein kinase zap-70 antibody, zeta-chain (TCR) associated protein kinase antibody, zeta chain of T cell receptor associated protein kinase 70 antibody, zeta-chain (TCR) associated protein kinase 70kDa antibody, zeta chain of T cell receptor associated protein kinase 70kDa L homeolog antibody, zeta chain of T cell receptor associated protein kinase 70kDa antibody, tyrosine-protein kinase ZAP-70 antibody, ZAP70 antibody, Smp_149470 antibody, Zap70 antibody, zap70.L antibody, zap70 antibody, LOC707555 antibody, LOC100342021 antibody, LOC100390922 antibody, LOC100542877 antibody

背景

Description:
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Aliases: SRK, STD, TZK, STCD, IMD48, ADMIO2, ZAP-70

分子量

69.9kDa

基因ID

7535

UniProt

P43403

途径

TCR Signaling, Ubiquitin Proteasome Pathway