LIFR 抗体 (AA 22-441)
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- 抗原 See all LIFR 抗体
- LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
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抗原表位
- AA 22-441
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LIFR antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD118 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli.
- 克隆位点
- 5D3G12
- 亚型
- IgG1
- Top Product
- Discover our top product LIFR Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
- 别名
- CD118 (LIFR 产品)
- 别名
- A230075M04Rik antibody, AW061234 antibody, LIF antibody, CD118 antibody, LIF-R antibody, SJS2 antibody, STWS antibody, SWS antibody, leukemia inhibitory factor receptor antibody, LIF receptor alpha antibody, leukemia inhibitory factor receptor alpha antibody, Lifr antibody, LOC397451 antibody, LIFR antibody
- 背景
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Description:
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.
Aliases: LIFR, SWS, SJS2, STWS, LIF-R
- 分子量
- 123.7kDa
- 基因ID
- 3977
- UniProt
- P42702
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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