NOXA 抗体 (AA 1-54)
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- 抗原 See all NOXA (PMAIP1) 抗体
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
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抗原表位
- AA 1-54
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NOXA antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- PMAIP1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. Coli.
- 克隆位点
- 1A2D3
- 亚型
- IgG1
- Top Product
- Discover our top product PMAIP1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
- 别名
- PMAIP1 (PMAIP1 产品)
- 别名
- TN3 antibody, PMAIP1 antibody, zgc:162379 antibody, APR antibody, NOXA antibody, Noxa antibody, phorbol-12-myristate-13-acetate-induced protein 1 antibody, PMAIP1 antibody, pmaip1 antibody, Pmaip1 antibody
- 背景
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Description:
The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Aliases: APR, NOXA
- 分子量
- 6kDa
- 基因ID
- 5366
- UniProt
- Q13794
- 途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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